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Centre for Pathogen Evolution

The Centre for Pathogen Evolution is based within the Department of Zoology, at the University of Cambridge. The Pathogen Evolution Group is dedicated to research in antigenically variable pathogens and pathogen evolution, and to contribute to basic science and critical issues in public health. We conduct highly translational scientific research focused on improving our understanding and ability to predict pathogen evolution in humans and other animals, provides support to the World Health Organization (WHO) influenza vaccine strain selection process, to the NIH SARS-CoV-2 Assessment of Viral Evolution (SAVE) and develop and distribute free high-quality software.

CID logo 2018


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Key Publications

Derek J. Smith, Alan S. Lapedes, et al, (2004). Mapping the Antigenic and Genetic Evolution of Influenza Virus Science 305(5682):371-376.

Colin A. Russell, Terry C. Jones, et al, (2008). The Global Circulation of Seasonal Influenza A (H3N2) Viruses Science 320(5874):340-346.

Björn F. Koel, David F. Burke, et al, (2013). Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution Science 342(6161):976-979.

J. M. Fonville, S. H. Wilks, et al, (2014). Antibody landscapes after influenza virus infection or vaccination Science 346(6212):996-1000

Samuel H. Wilks, Barbara Mühlemann et al, (2022) Mapping SARS-CoV-2 antigenic relationships and serological responses bioRxiv